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Comparative Effectiveness: Its Origin, Evolution, and Influence on Health Care

Physicians and payers alike are demonstrating increased interest in the use of evidence-based medicine (EBM), or implementation of treatments that have proven track records of delivering desired results in specific patient populations.¹ The cover story of Journal of Oncology Practice in November 2007, "Medicare's Coverage With Evidence Development: A Policy-Making Tool in Evolution,"¹ discussed how EBM is related to coverage with evidence development, defined as Medicare coverage for a treatment or technology on the basis of data collection through a clinical trial or registry. Essential to both EBM and coverage with evidence development is the concept of comparative effectiveness (CE), . . . [Click for More]

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