Journal of Oncology Practice, Vol 3, No 1 (January), 2007: pp. 1
© 2007
American Society of Clinical Oncology.
DOI: 10.1200/JOP.0710501
From Bench to Benchmarking
Douglas W. Blayney, MD
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Douglas W. Blayney, MD
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Would it surprise you to know that the first patients with Hodgkin's disease treated with MOPP (mustargen, vincristine, prednisone, procarbazine) were continually hospitalized in the National Cancer Institute Clinical Center for 6 months? MOPP is widely regarded as the first curative chemotherapy for a previously incurable adult malignancy. The regimen also served as the prototype for development of the cyclic cytotoxic chemotherapy regimens in use today, and for decades was a benchmark for the treatment of Hodgkin's disease. Thirty-three years later, MOPP's successor chemotherapies are infused in oncologist offices, and patients then recover in their own . . . [Click for More]

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